Abstract Background:- Depakine (valproic acid) is an antiepileptic medication that is commonly used as a first‑line treatment for a variety of seizures in both adults and children. However, it can result in testicular toxicity by increasing oxida tive stress inflammation. Melatonin (MLT) has antioxidant, anti‑inflammatory, and anti‑apoptotic potential. Therefore, the present study investigated the impact of MLT on depakine‑induced testicular damage in rats.

Clostridioides difficile is widely recognised as one of the most common causes of healthcare-associated C. difficile infections due to the ability of spores to survive for prolonged periods in the hospital environment. This study aimed to evaluate the efficacy of UV-C 254 nm light in the inactivation of the spores of different C. difficile ribotypes on brain heart infusion (BHI) agar plates or in phosphate-buffered saline (PBS) with varying spore densities. Furthermore, the effectiveness of a sporicidal surface disinfectant against C. difficile spores was determined on different surfaces. Spore suspensions of different C. difficile strains in the range of 10⁵–10⁷ colony-forming units (CFUs) mL⁻¹ were inoculated on BHI agar plates or in PBS and exposed to UV-C light for up to 30 min. Additionally, a spore suspension of 10³–10⁵ CFUs was spread over a 1 cm² test area on different surfaces, and sporicidal surface wipes were used according to the manufacturer’s instructions. The findings demonstrated that spores of C. difficile ribotypes exhibited a complete reduction in log₁₀ CFU on BHI agar plates and PBS following 20 min of exposure to a UV-C dose of 2208 mJ cm⁻². The surface wipes with sporicidal properties demonstrated efficacy in reducing the number of C. difficile spores on the Formica, stainless steel, and plastic surfaces by 2.03–3.53 log₁₀. The present study demonstrates that moist surfaces or liquids can enhance the efficacy of UV-C treatment in reducing C. difficile spores. This approach may be applicable to the surfaces of healthcare facilities and to water disinfection systems.

Abstract

For the first time in Libyan flora, a new record for Boerhavia repens L is recorded. This widespread wild weed was collected from the Ariggiba region (110 km west-south Sabha city). A full description, habitat information, distribution map, and distribution data are provided to facilitate further identification and future detection. A brief discussion about the most important threats this species poses is presented.

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Synthesizing silver nanoparticles (AgNPs) from extracts of various plant parts

and of agricultural waste is strongly affected by pH. These green synthesis

methods cconsidered simple, cost effective, ecofriendly, and biologically

effective. This brief review aimed to survey the role of pH in the green

synthesis of AgNPs using those media, with a focus on its effect on AgNPs

morphology and size. This review article revealed that the alkaline pH (9 -

10) is the optimum condition for synthesizing more stable and tiny uniform

AgNPs. In addition, according to the reviewed articles, the spherical shape is

the most dominant shape of these articles in the basic medium and the size of

these particles decreases at elevated pH values and ranged from 5-40 nm.

This research presents the wireless university campus network and discusses about the strengths and weaknesses of Design a secure wireless campus networks for ABC University in Libya, and about the costs and advantages of different vendor solutions. Wireless offers mobility and is available in locations where a wired outlet doesn't exist. The disadvantages of wireless include some minor interference problems and a quickly evolving and competitive group of standards. The purpose of the research is designing and implementing a secure campus network for Libyan university based on Cisco equipments. Moreover, the research can provide practical experience in network design, configuration, and security for helping organizations and institutions protect their network resources and data. Two end products or deliverables will result from the research: the first is a new architectural design for an efficient and advanced WLAN-friendly network to ensure the high performance of the data transaction process and ensure high availability of data transmissions. The second product is a report for network administrators or network architecture to guide users towards the achievement of WLAN-friendly by utilising advanced networking tools and technologies.

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