Diabetes mellitus is a growing global health concern, characterized by chronic hyperglycemia, resulting from defective insulin action and secretion, T2DM is frequently associated with abnormalities in the liver function, which may reflect underlying metabolic disturbances and early hepatic involvement. This study aimed to evaluate the levels of liver aminotransferase ( ALT, AST) and ALP in patients with type 2 diabetes in Gharyan central hospital. The finding showed that patients with T2DM had elevated liver enzyme levels, (ALT, AST and ALP were 19%, 15%, 41% respectively), suggesting possible subclinical liver dysfunction. These results highlight the importance of routine liver enzyme assessment in the clinical follow up of individuals with T2DM, as early detection of hepatic abnormalities may improve patient management and reduce the risk of diabetes- related complications. 

Abstract Background: Acute respiratory tract infections (ARTIs) remain one of the leading causes of morbidity and Published: June 15, 2026 hospitalization among preschool children worldwide. particularly in low- and middle- income countries. Vitamin D plays a crucial immunomodulatory role in respiratory health by enhancing innate immunity and maintaining epithelial barrier integrity. However, vitamin D deficiency is highly prevalent among children, including those living in sun- rich regions such as Libya. Objectives: This study aimed to assess serum vitamin D levels among preschool children admitted with ARTIs at Gharyan Central Teaching Hospital and to evaluate the association between vitamin D status, disease severity, and recurrence. Methods: A cross-sectional observation study was conducted among 100 preschool children aged 1-6 years admitted with clinically diagnosed ARTIs between January and December 2025. After applying the inclusion and exclusion criteria, 79 eligible participants were included in the final analysis. Serum 25-hydroxyvitamin D [25(OH)D] levels were measured and categorized according to Endocrine Society guidelines. Associations between vitamin D levels, ARTIs severity, and recurrence were analysed using chi-square tests and logistic regression models. Results: Vitamin D deficiency and insufficiency were highly prevalent, affecting 87.3% of the studied children. Although lower vitamin D levels were more frequently observed among children with moderate and severe ARTIs, the association with disease severity was not statistically significant (p=0.115). In contrast, a significant association was identified between low vitamin D levels and recurrent ARTIs (p=0.019). Conclusion: Vitamin D deficiency is highly prevalent among preschool children hospitalized with ARTIs and is significantly associated with recurrent infections. Improving vitamin D status may contribute to reducing the recurrence of ARTIs in this population.

Medical education is being reshaped by two major technological disruptions: the rapid expansion of online learning since the COVID-19 pandemic and the equally rapid adoption of artificial intelligence (AI) in teaching, assessment, and clinical training. These developments are often treated as distinct phases of change. In reality, they are part of the same broader challenge: educational institutions have repeatedly adopted new technologies faster than they have developed the pedagogic, ethical, and regulatory frameworks needed to use them well. 1-3

This study aimed to evaluate the inhibitory and lethal effects of root extracts of the Wild Rue plant (Peganum harmala L.) against the pathogenic fungus Rhizoctonia solani under laboratory conditions. Two types of extracts (aqueous and alcoholic) were used at concentrations of (5%, 10%, 15%, and 20%). The results indicated that the effectiveness increased proportionally with the concentration. The inhibition rate of the aqueous extract reached 64.8% at a concentration of 20%, while the alcoholic extract was significantly superior, reaching 84% at the same concentration. Statistical analysis confirmed highly significant differences between concentrations (P < 0.001) as determined by one-way ANOVA, while two-way ANOVA showed extract type, concentration, and their interaction were significant factors, explaining approximately 85% of the total variance. The study concluded that the alcoholic extract is more effective than the aqueous one in inhibiting R. solani, making it a promising option for fungal control as a safe alternative to chemical pesticides.